Census Population Change, 1990–2000
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| Population, April 1, 1990 | Population, April 1, 2000 | Numeric Population Change, 1990 to 2000 | Percent Population Change, 1990 to 2000 | Land Area (square miles), 2000 | Persons Per Square Mile, 1990 | Persons Per Square Mile, 2000 | |
| United States | 248,709,873 | 281,421,906 | 32,712,033 | 13.2% | 3,537,438.4 | 70.3 | 79.6 |
| Appalachian Region | 21,727,579 | 23,642,578 | 1,914,999 | 8.8% | 204,812.1 | 106.1 | 115.4 |
| STATE TOTALS | |||||||
| Alabama | 4,040,587 | 4,447,100 | 406,513 | 10.1% | 50,744.0 | 79.6 | 87.6 |
| Georgia | 6,478,216 | 8,186,453 | 1,708,237 | 26.4% | 57,906.1 | 111.9 | 141.4 |
| Kentucky | 3,685,296 | 4,041,769 | 356,473 | 9.7% | 39,728.2 | 92.8 | 101.7 |
| Maryland | 4,781,468 | 5,296,486 | 515,018 | 10.8% | 9,773.8 | 489.2 | 541.9 |
| Mississippi | 2,573,216 | 2,844,658 | 271,442 | 10.5% | 46,907.0 | 54.8 | 60.6 |
| New York | 17,990,455 | 18,976,457 | 986,002 | 5.5% | 47,213.8 | 381.0 | 401.9 |
| North Carolina | 6,628,637 | 8,049,313 | 1,420,676 | 21.4% | 48,710.9 | 136.1 | 165.2 |
| Ohio | 10,847,115 | 11,353,140 | 506,025 | 4.7% | 40,948.4 | 264.9 | 277.3 |
| Pennsylvania | 11,881,643 | 12,281,054 | 399,411 | 3.4% | 44,816.6 | 265.1 | 274.0 |
| South Carolina | 3,486,703 | 4,012,012 | 525,309 | 15.1% | 30,109.5 | 115.8 | 133.2 |
| Tennessee | 4,877,185 | 5,689,283 | 812,098 | 16.7% | 41,217.1 | 118.3 | 138.0 |
| Virginia | 6,187,358 | 7,078,515 | 891,157 | 14.4% | 39,594.1 | 156.3 | 178.8 |
| West Virginia | 1,793,477 | 1,808,344 | 14,867 | 0.8% | 24,077.7 | 74.5 | 75.1 |
| STATE APPALACHIAN TOTALS | |||||||
| Click on the links below to get information on that state's Appalachian Counties. | |||||||
| Appalachian Alabama | 2,570,049 | 2,837,224 | 267,175 | 10.4% | 25,827.9 | 99.5 | 109.9 |
| Appalachian Georgia | 1,546,691 | 2,207,531 | 660,840 | 42.7% | 11,421.1 | 135.4 | 193.3 |
| Appalachian Kentucky | 1,088,416 | 1,160,627 | 72,211 | 6.6% | 18,302.4 | 59.5 | 63.4 |
| Appalachian Maryland | 224,477 | 236,699 | 12,222 | 5.4% | 1,531.5 | 146.6 | 154.6 |
| Appalachian Mississippi | 565,014 | 615,452 | 50,438 | 8.9% | 12,393.1 | 45.6 | 49.7 |
| Appalachian New York | 1,088,470 | 1,072,786 | -15,684 | -1.4% | 11,698.4 | 93.0 | 91.7 |
| Appalachian North Carolina | 1,306,682 | 1,526,207 | 219,525 | 16.8% | 11,900.9 | 109.8 | 128.2 |
| Appalachian Ohio | 1,965,333 | 2,040,712 | 75,379 | 3.8% | 16,010.2 | 122.7 | 127.5 |
| Appalachian Pennsylvania | 5,769,410 | 5,819,800 | 50,390 | 0.9% | 36,488.8 | 158.1 | 159.5 |
| Appalachian South Carolina | 888,057 | 1,028,656 | 140,599 | 15.8% | 3,834.0 | 231.5 | 268.3 |
| Appalachian Tennessee | 2,191,542 | 2,530,610 | 339,068 | 15.5% | 20,116.9 | 60.1 | 125.8 |
| Appalachian Virginia | 729,961 | 757,930 | 27,969 | 3.8% | 11,209.2 | 36.3 | 67.6 |
| Appalachian West Virginia | 1,793,477 | 1,808,344 | 14,867 | 0.8% | 24,077.7 | 74.5 | 75.1 |