The Appalachian Development Highway System (ADHS) is a network of 33 distinct highway corridors totaling 3,090 miles and connecting the 13 Appalachian states with the Interstate Highway System and a wide-range of domestic and global markets. As of February 2018, these corridors and termini are a part of the ADHS.

Corridor A (Georgia, North Carolina)

From I-285 north of Atlanta, GA, to I-40 near Clyde, NC

Existing Route
GA – US 19, SR 5
NC – US64, US 19A

Corridor A-1 (Georgia)

From Corridor A south of Cumming, GA, to Intersection SR 53 north of Dawson and Forsyth County line

Existing Route
US19

Corridor A-2 (Georgia)

From Corridor A east of Canton, GA, to I-75 near Cartersville, GA

Existing Route
SR 20

Corridor B (North Carolina, Tennessee, Virginia, Kentucky, Ohio)

From Intersection of I-26 and I-40 at Asheville, NC, to Corridor C north of Portsmouth, OH

Existing Routes
NC – US 23
TN – US 52
VA – SR 348
KY – SR 73

Corridor B-1 (Kentucky, Ohio)

From Corridor B near Greenup Dam, KY, to Corridor B north of Portsmouth, OH

Existing Routes
KY – US 23

Corridor C (Ohio)

From Corridor B north of Portsmouth, OH, to I-270 south of Columbus, OH

Existing Routes
US 23

Corridor C-1 (Ohio)

From Corridor D near Jackson, OH, to Corridor C at Chillicothe, OH

Existing Routes
US 35

Corridor D (Ohio, West Virginia)

From I-275 east of Cincinnati, OH, to I-79 near Bridgeport, WV

Existing Routes
OH – SR 32
WV – SR 124, US 50

Corridor E (West Virginia, Maryland)

From I-79 near Morgantown, WV, to I-70 near Hancock, MD

Existing Routes
WV – SR 73
MD – US 40

Corridor F (Tennessee, Kentucky)

From I-75 near Caryville, TN, to Corridor B near Jenkins, KY

Existing Routes
TN – US 25W, SR 63
KY – US 25E, US 119

Corridor G (Kentucky, West Virginia)

From Corridor B near Pikeville, KY, to I-64 near Charleston, WV

Existing Routes
KY – US 119

Corridor H (West Virginia, Virginia)

From I-79 near Weston, WV, to I-81 near Strasburg, VA

Existing Routes
WV – US 23
VA – US 220, SR 55

Corridor I (Kentucky)

From Corridor F near Whitesburg, KY, to I-64 near Winchester, KY

Existing Routes
SR 15

Corridor J ( Tennessee, Kentucky)

From I-24 near Chattanooga, TN, to I-75 near London, KY

Existing Routes
TN – SR 8, SR 53
KY – SR 61, SR 90, SR 80

Corridor J-1 (Tennessee)

From Algood City Limits to Corridor J near Gainsboro, TN

Existing Routes
PSR 451, SR 56

Corridor K (Tennessee, North Carolina)

From I-75 near Cleveland, TN, to Corridor A near Dillsboro, NC

Existing Routes
TN – US 64
NC – US 19, US 19A

Corridor L (West Virginia)

From I-77 near Beckley, WV, to I-79 near Sutton, WV

Existing Routes
US 19

Corridor M (Pennsylvania)

From I-70/I-76 at New Stanton, PA, to I-81 near Harrisburg, PA

Existing Routes
US 22

Corridor N (Maryland, Pennsylvania)

From Corridor E near Grantsville, MD, to Corridor M at Ebensburg, PA

Existing Routes
MD – US 219

Corridor O (Maryland, Pennsylvania)

From Corridor E near Cumberland, MD, to I-80 near Belfonte, PA

Existing Routes
MD – US 220

Corridor O-1 (Pennsylvania)

From Corridor O at Port Matilda, PA, to I-80 near Clearfield, PA

Existing Routes
US 322

Corridor P (Pennsylvania)

From I-80 near Mackeyville, PA, to I-80 near Milton, PA

Existing Routes
SR 147
US 220

Corridor P-1 (Pennsylvania)

From Corridor M near New Buffalo, PA, to Corridor P near Milton, PA

Existing Routes
SR 147

Corridor Q (Kentucky, Virginia, West Virginia)

From Corridor B near Shelbiana, KY, to I-81 near Christiansburg, VA

Existing Routes
KY – SR 80
VA – SR 609
WV – US 460

Corridor R (Kentucky)

From Corridor I near Campton, KY, to Corridor B at Prestonburg, KY

Existing Routes
KY Mountain Pkwy.

Corridor S (Tennessee)

From I-81 north of White Pine, TN, to Corridor F south of Harrogate, TN

Existing Routes
US 25E

Corridor T (Pennsylvania, New York)

From I-90 east of Erie, PA, to I-81 near Binghamton, NY

Existing Routes
PA – SR 430
NY – SR 17

Corridor U (Pennsylvania, New York)

From Corridor P near Williamsport, PA, to Corridor T near Elmira, NY

Existing Routes
PA – US 15, SR 328
NY – SR 328

Corridor U-1 (Pennsylvania, New York)

From Interchange with PA 328 to SR 17/I-86

Existing Routes
PA – US 15

Corridor V (Mississippi, Alabama, Tennessee)

From I-55 near Batesville, MS, to I-24 west of Chattanooga, TN

Existing Routes
MS – SR 6, SR 24, I-565
AL – US 72
TN – US 72

Corridor W (South Carolina, North Carolina)

From I-85 near Greenville, SC, to I-26 near Hendersonville, NC

Existing Routes
SC – US 25 Bypass
NC – US 25

Corridor X (Mississippi, Alabama)

From Corridor V near Fulton, MS, to I-59 near Birmingham, AL

Existing Routes
MS – US 78
AL – US 78

Corridor X-1 (Alabama)

From I-459 near Birmingham, AL, to I-20 near Leeds, AL